产品货号：
Z38052
中文名称：
FER抗体
英文名称：
Anti-FER Antibody (Clone#5D2C4)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FER Antibody (Clone#5D2C4) |
| 指标别名 | FER;p94 Fer;Proto oncogene c Fer;TYK3;Tyrosine kinase 3;Tyrosine protein kinase Fer |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,IF |
| 基因名称 | FER |
| 克隆号 | 5D2C4 |
| 抗体来源 | Mouse |
| 免疫原 | Purified recombinant fragment of human Fer expressed in E.Coli. |
| 计算分子量 | 95KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Ascitic fluid |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | FER(FPS/FES-Related tyrosine kinase) also known as TYK3,is an enzyme that in humans is encoded by the FER gene.Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases.By in situ hybridization,Morris et al.(1990) concluded that the FER gene is located at 5q21-q22.Treatment of cells with JMP resulted in the release of FER from the cadherin complex and its accumulation in the integrin complex.The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER.The results suggested that FER mediates crosstalk between CDH2 and ITGB1.In Fer mutant mice,leukocyte emigration was exaggerated in response to LPS without altering vascular permeability,suggesting that FER has a role in regulating innate immunity. |
| Uniprot ID | P16591 |
| 基因名全称 | Tyrosine-protein kinase Fer |
| 推荐稀释比 | WB,1:500～1:2000 IHC,1:200～1:1000 IF,1:200～1:1000 |
相关搜索：FER抗体，FER单抗，Anti-FER Antibody (Clone#5D2C4)